Darouiche ro, wall mj, itani kmf et al chlorhexidine-alcohol versus povidone- iodine for surgical site antisepsis new eng j med 2010362(1):18-26 2 guyatt gh. Povidone iodine 10 %, chlorhexidine 2 % in 70 % alcohol and iodine povacrylax in alcohol were used in three different phases of the study although the final result favored iodine povacrylax in reducing ssis, the odds ratio between pvi and chg favored pvi in preventing ssi (or = 106. The present study was undertaken to compare and evaluate the efficacy of chlorhexidine alcohol versus povidone iodine in elective clean surgeries for prevention of ssi.
Chlorhexidine-alcohol versus povidone-iodine as preoperative skin preparation to prevent surgical site infection: a meta-analysis. Abstract chlorhexidine-alcohol versus povidone-iodine for surgical-site antisepsis background since the patient's skin is a major source of pathogens that cause surgical-site infection, optimization of preoperative skin antisepsis may decrease postoperative infections. Research article open access skin asepsis protocols as a preventive measure of surgical site infections in dogs: chlorhexidine-alcohol versus povidone-iodine. Historically, antiseptic agents progressed from the age of alcohol and phenol to hexachlorophene, then povidone iodine followed by chlorhexidine gluconate agents with each agent having a distinct advantage.
Chlorhexidine-alcohol has rapid lethal action against both transient and resident flora, especially on anaerobic bacteriatherefore it can be safely concluded that chlorhexidine-alcohol can be used for preoperative skin preparation as an alternative to povidone-iodine in clean and clean-contaminated surgeries. Comparison of chlorhexidine-alcohol and povidone-iodine for 10% povidone-iodine versus 05% chlorhexidine-alcohol a total of 2,755 samples were obtained. Tions according to the cdc2 the infection rate for the 10% povidone-iodine protocol was 146% vs 45% ssi rate for the 2% chlorhexidine protocol (p¼0011) when grouped for all. The primary outcome was the incidence of catheter-related infections with chlorhexidine-alcohol versus povidone iodine-alcohol in the intention-to-treat population. Summary: it appears from several studies, meta-analysis, and use across several different indications, that topical chlorhexidine-gluconate-70% isopropyl alcohol solution applied to the skin is more effective than povidone-iodine (betadine) at preventing skin or wound infections when used prior to an invasive or surgical procedure.
The myriad of sterile preparation solutions at this institution are betadine (10% povidone iodine), hibiclens (chlorhexidine gluconate), and chlorhexidine alcohol current pre-operative skin preparation with one of these solutions is largely dictated by what is available, in close proximity, or surgeon preference. From the pilot data the proportion of patients with swc was 27% in the 05% chlorhexidine/70% alcohol group versus 8% of patients in the 10% povidone iodine (1% available iodine)/70% alcohol group. Original investigation chlorhexidine-based antiseptic solution vs alcohol-based povidone-iodine alcohol-based povidone-iodine chlorhexidine.
Preoperative skin antisepsis with chlorhexidine gluconate versus povidone-iodine: a prospective analysis of 6959 consecutive spinal surgery patients alcohol) and. The pros and cons of scrubbing with betadine, chlorhexidine with a povidone iodine or chlorhexidine spray povidone solution, alcohol, chlorhexidine scrub and. Backgroundalthough chlorhexidine-based solutions and alcohol-based povidone-iodine have been shown to be more efficient than aqueous povidone-iodine for skin di. 2% chlorhexidine-70% isopropyl alcohol versus 10% povidone-iodine for insertion site cleaning before central line insertion in preterm infants: a randomised trial free emily a kieran 1 , 2 , 3 .
Chlorhexidine gluconate versus povidone-iodine as vaginal preparation antiseptics prior to cesarean delivery the safety and scientific validity of this study is the responsibility of the study sponsor and investigators. A comparison of chlorhexidine-alcohol versus povidone-iodine for eliminating skin flora before genitourinary prosthetic surgery: a randomized controlled trial. Alcohol formulations of chlorhexidine and povidone are commonly used for skin antisepsis before intravascular catheter insertion to assess whether one is superior to the other and whether scrubbing the skin improves outcomes, investigators (with partial industry support) conducted a multicenter, open-label trial involving patients in medical and surgical intensive care units in france. It is actually a comparison of chlorhexidine plus alcohol (ie 2 antiseptics) vs povidone-iodine alone (ie one antiseptic) on microbiological grounds, the alcohol is about 10 times stronger than either chlorhexidine or podidone-iodine alone.